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Thyroid hormone therapy: patients with hypothyroidism are most often treated with Levothyroxine in order to return their thyroid hormone levels to normal. Replacement therapy means the goal is a TSH in the normal range and is the usual therapy. Suppressive therapy means that the goal is a TSH below the normal range and is used in thyroid cancer patients to prevent growth of any remaining cancer cells.
Twitter feed Tweets by thyroidfriends. Patient Publications. Connect with Us. Patient Calendar of Events. Find a Thyroid Specialist. National Center for Biotechnology Information , U. Journal List J Thyroid Res v. J Thyroid Res. Published online Jul Author information Article notes Copyright and License information Disclaimer.
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This article has been cited by other articles in PMC. Introduction Hypothyroidism is a common endocrine disorder resulting from deficiency of thyroid hormone.
Statistical Analysis Primary end point was a change in the thyroid profile of the subjects and achievement of euthyroidism in each group measured at the end of six and 12 weeks. Observations and Results The mean age of patients in group 1 was Open in a separate window.
Discussion The present study shows noninferiority of the evening dose of levothyroxine when compared to the morning dose in terms of improvement in signs and symptoms, quality of life, and dosage of the drug required for achievement of euthyroidism. References 1. Wiersinga WM. Subclinical hypothyroidism and hyperthyroidism. Prevalence and clinical relevance. Netherlands Journal of Medicine. The incidence of thyroid disorders in the community: a twenty year follow up of Whickham survey.
Clinical Endocrinology. Replacement dose, metabolism, and bioavailability of Levothyroxine in the treatment of hypothyroidism. The New England Journal of Medicine.
Sucralfate causes malabsorption of L-thyroxine. American Journal of Medicine. Effect of calcium carbonate on the absorption of levothyroxine. Journal of the American Medical Association. Ferrous sulfate reduces thyroxine efficacy in patients with hypothyroidism. Annals of Internal Medicine.
Raloxifene causing malabsorption of levothyroxine. Archives of Internal Medicine. Evidence for a clinically important adverse effect of fiber-enriched diet on the bioavailability of levothyroxine in adult hypo- thyroid patients. Altered intestinal absorption of L-thyroxine caused by coffee. Effects of evening vs morning thyroxine ingestion on serum thyroid hormone profiles in hypothyroid patients. Summary and discussion of MOS measures.
In: Stewart AL, editor. Statistical methods applied to the diagnosis of hypothyroidism. The Quarterly Journal of Medicine. Prolonged ambulatory antroduodenal manometry in humans. American Journal of Gastroenterology. Hays MT. Localization of human thyroxine absorption. L-thyroxin absorption in patients with short bowel.
The influence of circulating thyroxine serum concentration on hepatic thyroxine deiodinating activity in rats. Experimental and Clinical Endocrinology. Timing of levothyroxine administration affects serum thyrotropin concentration. Effects of evening vs morning levothyroxine intake. Physiological regulation of circadian and pulsatile thyrotropin secretion in normal man and woman. Journal of Clinical Endocrinology and Metabolism.
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